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Yellow Mouth Disease treatment protocol — 2026 update

Yellow Mouth Disease — distinct yellowing of mouth area, atrophied liver, weak feeding. Combined protocol: water disinfection + liver recovery + immunity boost.

Yellow Mouth Disease is common but easily confused with general weak hepatopancreas. Key signs: deep yellow mouth area, reduced feeding, atrophied liver. Often related to Vibrio and environmental toxins — requires a 3-front combined protocol: water disinfection + liver recovery + immunity boost.

1. Recognizing Yellow Mouth Disease

Differentiate from general weak hepatopancreas:

  • Deep yellow mouth area — most distinctive sign.
  • Reduced or refused feeding, empty gut.
  • Atrophied pale liver, possible black spots on shell.
  • Sporadic mortality 5 – 20% if untreated.
  • Usually appears day 30 – 60 in Vibrio-history ponds.

2. 7-day treatment protocol

Apply immediately on symptom confirmation:

  • Day 1 – 2: broadcast VIBRIO CLEAR, cut feed 50%.
  • Day 3 – 7: feed CLEVER 5 g/kg + HERB GUARD 7 ml/kg + AQUAMOS 3 g/kg, 3 meals/day.
  • Day 4: reseed water probiotics (SOILMAX or MAX 4000).
  • After day 7: switch to CLEVER 3 g/kg + HEPA PRO 5 ml/kg maintenance 5 days.
  • Boost DO ≥ 5 ppm, monitor NH₃/NO₂ daily.

3. Recurrence prevention

  • Prevention from day 15: CLEVER 2 – 3 g/kg + HERBAL GOLD 3 ml/kg in feed.
  • Broadcast SOILMAX or MAX 4000 every 3 – 5 days to keep Vibrio below threshold.
  • Monitor green Vibrio on TCBS weekly.
  • Avoid sudden > 30% water exchange — creates background stress that lets disease return.

Suspect Yellow Mouth Disease — need rapid-response protocol?

Send shrimp photos + pond parameters via Zalo 0867 957 568 — Than Vuong confirms diagnosis and sends protocol in 1h.

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