🧬 Scientific foundation

The science behind Microbiome Farm Protocol

Every Than Vuong product is grounded in international microbial science consensus — ISAPP and peer-reviewed shrimp research. This page summarises Postbiotic / Probiotic / Prebiotic distinction, microbe glossary, and citation library.

Section 1

Postbiotic — Probiotic — Prebiotic: 3 distinct concepts

Farmers often lump these as “probiotics”. ISAPP — International Scientific Association for Probiotics and Prebiotics — defines 3 distinct concepts:

Probiotic

Live beneficial microbes

Live microorganisms which, when administered in adequate amounts, confer a health benefit on the host. Common strains: Bacillus subtilis, Lactobacillus, Pediococcus.

Than Vuong products:MAX 4000SOILMAXPRO GUTLALSEA BIOREM
📜 ISAPP consensus 2014

Prebiotic

Substrate for beneficial microbes

A substrate that is selectively utilized by host microorganisms conferring a health benefit. Includes: MOS (mannan-oligosaccharide), beta-glucan, FOS, inulin.

Than Vuong products:AQUAMOSBETAGLUCAN GRO
📜 ISAPP consensus 2017

Postbiotic

Postbiotic — inactive cells + metabolites

Preparation of inanimate microorganisms and/or their components that confers a health benefit on the host. Does NOT require live microbes.

Than Vuong products:BIOMAX
📜 ISAPP consensus 2021
Section 2

Important microbe glossary

Strains in Than Vuong products and common pathogens in shrimp farming.

Latin nameRoleType
Bacillus subtilisProduces digestive enzymes, suppresses Vibrio, stabilizes pond bottomBeneficial
Bacillus licheniformisDecomposes proteins, reduces NH3/H2SBeneficial
Lactobacillus plantarumGut probiotic, produces lactic acid, lowers gut pHBeneficial
Pediococcus acidilacticiAdheres to gut lining, displaces pathogensBeneficial
Saccharomyces cerevisiae boulardiiYeast balances gut, supports recovery after antibioticsBeneficial
Bifidobacterium spp.Innate beneficial bacteria, thrive with postbioticBeneficial
Vibrio parahaemolyticusPATHOGEN — EMS/AHPND, acute hepatopancreas necrosisPathogen
Vibrio harveyiPATHOGEN — luminous vibriosis (glowing shrimp at night)Pathogen
Enterocytozoon hepatopenaei (EHP)PATHOGEN — microsporidian, causes slow growth & white fecesPathogen
Section 3

Scientific research library

Peer-reviewed research underpinning Microbiome Farm Protocol and Than Vuong products.

  1. 1

    Whiteleg shrimp gut microbiome — metagenomics analysis

    Cornejo-Granados et al. · 2017 · Scientific Reports

    Foundation: classifies shrimp gut microbiota — beneficial vs opportunistic vs pathogenic

    DOI: 10.1038/s41598-017-11805-w
  2. 2

    Etiology of white feces syndrome (WFS) in Penaeus vannamei

    Aranguren et al. · 2021 · Aquaculture

    Multi-causal: EHP + Vibrio + parasites. Not a single pathogen.

    DOI: 10.1016/j.aquaculture.2020.736035
  3. 3

    ISAPP consensus definition of Postbiotic

    Salminen et al. (ISAPP) · 2021 · Nature Reviews Gastroenterology & Hepatology

    Official standard for Postbiotic — applies to BIOMAX

    DOI: 10.1038/s41575-021-00440-6
  4. 4

    ISAPP consensus definition of Probiotic

    Hill et al. (ISAPP) · 2014 · Nature Reviews Gastroenterology & Hepatology

    Standard for Probiotic — live beneficial microbes

    DOI: 10.1038/nrgastro.2014.66
  5. 5

    ISAPP consensus definition of Prebiotic

    Gibson et al. (ISAPP) · 2017 · Nature Reviews Gastroenterology & Hepatology

    Standard for Prebiotic — substrates for beneficial microbes

    DOI: 10.1038/nrgastro.2017.75
  6. 6

    TPD (Translucent Postlarvae Disease) — emerging Vibrio pathogen

    Zou et al. · 2020 · Aquaculture

    TPD — new postlarvae disease threatening global shrimp industry

    DOI: 10.1016/j.aquaculture.2020.735581

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